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Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

BACKGROUND: Pax6 is a transcription factor essential for normal development of the eyes and nervous system. It has two major isoforms, Pax6 and Pax6(5a), and the ratios between their expression levels vary within narrow limits. We tested the effects of overexpressing either one or other isoform on e...

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Bibliografiske detaljer
Main Authors: Pinson, Jeni, Simpson, T Ian, Mason, John O, Price, David J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489926/
https://ncbi.nlm.nih.gov/pubmed/16725027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-6-25
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