Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

Eitemau Tebyg

• Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells
  gan: Pinson, Jeni, et al.
  Cyhoeddwyd: (2006)
• The Generation of Superficial Cortical Layers Is Regulated by Levels of the Transcription Factor Pax6
  gan: Georgala, Petrina A., et al.
  Cyhoeddwyd: (2011)
• Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain
  gan: Pinson, Jeni, et al.
  Cyhoeddwyd: (2005)
• Long-range downstream enhancers are essential for Pax6 expression
  gan: Kleinjan, Dirk A., et al.
  Cyhoeddwyd: (2006)
• Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism
  gan: Quinn, Jane C., et al.
  Cyhoeddwyd: (2007)