Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

Levels of expression of the transcription factor Pax6 vary throughout corticogenesis in a rostro-lateral(high) to caudo-medial(low) gradient across the cortical proliferative zone. Previous loss-of-function studies have indicated that Pax6 is required for normal cortical progenitor proliferation, ne...

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Xehetasun bibliografikoak
Egile Nagusiak: Manuel, Martine, Georgala, Petrina A., Carr, Catherine B., Chanas, Simon, Kleinjan, Dirk A., Martynoga, Ben, Mason, John O., Molinek, Michael, Pinson, Jeni, Pratt, Thomas, Quinn, Jane C., Simpson, T. Ian, Tyas, David A., van Heyningen, Veronica, West, John D., Price, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386558/
https://ncbi.nlm.nih.gov/pubmed/17202185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02764
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