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Pax6 Represses Androgen Receptor-Mediated Transactivation by Inhibiting Recruitment of the Coactivator SPBP

The androgen receptor (AR) has a central role in development and maintenance of the male reproductive system and in the etiology of prostate cancer. The transcription factor Pax6 has recently been reported to act as a repressor of AR and to be hypermethylated in prostate cancer cells. SPBP is a tran...

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Detalhes bibliográficos
Main Authors: Elvenes, Julianne, Thomassen, Ernst Ivan Simon, Johnsen, Sylvia Sagen, Kaino, Katrine, Sjøttem, Eva, Johansen, Terje
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174178/
https://ncbi.nlm.nih.gov/pubmed/21935435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024659
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