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Lewis acid-promoted α-hydroxy β-dicarbonyl to α-ketol ester rearrangement

The decarbomethoxylation reaction of a substituted α-hydroxy-α-carbomethoxy pentacyclic substituted ketone, used as an advanced intermediate in the synthesis of the alkaloid aspidophytine, can be elected by heating with MgI(2) in CH(3)CN. The reaction was shown to proceed by a novel α-hydroxy β-dica...

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Autors principals: Hong, Xuechuan, Mejía-Oneto, José M., Padwa, Albert
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805679/
https://ncbi.nlm.nih.gov/pubmed/17330147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.09.071
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