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Lewis acid-promoted α-hydroxy β-dicarbonyl to α-ketol ester rearrangement

The decarbomethoxylation reaction of a substituted α-hydroxy-α-carbomethoxy pentacyclic substituted ketone, used as an advanced intermediate in the synthesis of the alkaloid aspidophytine, can be elected by heating with MgI(2) in CH(3)CN. The reaction was shown to proceed by a novel α-hydroxy β-dica...

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Detalhes bibliográficos
Main Authors: Hong, Xuechuan, Mejía-Oneto, José M., Padwa, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805679/
https://ncbi.nlm.nih.gov/pubmed/17330147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.09.071
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