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Lewis acid-promoted α-hydroxy β-dicarbonyl to α-ketol ester rearrangement

The decarbomethoxylation reaction of a substituted α-hydroxy-α-carbomethoxy pentacyclic substituted ketone, used as an advanced intermediate in the synthesis of the alkaloid aspidophytine, can be elected by heating with MgI(2) in CH(3)CN. The reaction was shown to proceed by a novel α-hydroxy β-dica...

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Bibliografiske detaljer
Main Authors: Hong, Xuechuan, Mejía-Oneto, José M., Padwa, Albert
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805679/
https://ncbi.nlm.nih.gov/pubmed/17330147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.09.071
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