A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer

Progress toward the understanding and management of human colon cancer can be significantly advanced if appropriate experimental platforms become available. We have investigated whether a rat model carrying a knockout allele in the gatekeeper gene Adenomatous polyposis coli (Apc) recapitulates famil...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Amos-Landgraf, James M., Kwong, Lawrence N., Kendziorski, Christina M., Reichelderfer, Mark, Torrealba, Jose, Weichert, Jamey, Haag, Jill D., Chen, Kai-Shun, Waller, Jordy L., Gould, Michael N., Dove, William F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805486/
https://ncbi.nlm.nih.gov/pubmed/17360473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611690104
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