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The utility of Apc-mutant rats in modeling human colon cancer

Prior to the advent of genetic engineering in the mouse, the rat was the model of choice for investigating the etiology of cancer. Now, recent advances in the manipulation of the rat genome, combined with a growing recognition of the physiological differences between mice and rats, have reignited in...

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Bibliografiska uppgifter
Huvudupphovsmän: Irving, Amy A., Yoshimi, Kazuto, Hart, Marcia L., Parker, Taybor, Clipson, Linda, Ford, Madeline R., Kuramoto, Takashi, Dove, William F., Amos-Landgraf, James M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Limited 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213726/
https://ncbi.nlm.nih.gov/pubmed/25288683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.016980
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