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A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer

Progress toward the understanding and management of human colon cancer can be significantly advanced if appropriate experimental platforms become available. We have investigated whether a rat model carrying a knockout allele in the gatekeeper gene Adenomatous polyposis coli (Apc) recapitulates famil...

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Bibliografski detalji
Glavni autori: Amos-Landgraf, James M., Kwong, Lawrence N., Kendziorski, Christina M., Reichelderfer, Mark, Torrealba, Jose, Weichert, Jamey, Haag, Jill D., Chen, Kai-Shun, Waller, Jordy L., Gould, Michael N., Dove, William F.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805486/
https://ncbi.nlm.nih.gov/pubmed/17360473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611690104
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