טוען...
A kindred with Mutant IKAROS and autoimmunity.
IKAROS (encoded by IKZF1) is an important hematopoietic transcription factor critical for early B cell differentiation, with major defects known to lead to low B cell numbers and hypogammaglobulinemia. More perplexing is the link between IKZF1 variants and autoimmunity, including polymorphisms assoc...
שמור ב:
| הוצא לאור ב: | J Allergy Clin Immunol |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541477/ https://ncbi.nlm.nih.gov/pubmed/29705243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.04.008 |
| תגים: |
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