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Regulation of B cell fate commitment and immunoglobulin V(H) gene rearrangements by Ikaros
The transcription factor Ikaros is essential for B cell development. However, its molecular functions in B cell fate specification and commitment have remained elusive. We showed that the transcription factor EBF rescued the generation of CD19(+) pro-B cells from Ikzf1(-/-) hematopoietic progenitors...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699484/ https://ncbi.nlm.nih.gov/pubmed/18568028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1626 |
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