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Differential regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros

C2H2 zinc fingers are found in several transcriptional regulators in the immune system. However, these proteins usually contain more fingers than are needed for stable DNA binding, suggesting that different fingers regulate different genes and functions. Mice lacking finger 1 or finger 4 of Ikaros e...

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Detalhes bibliográficos
Main Authors: Schjerven, Hilde, McLaughlin, Jami, Arenzana, Teresita L., Frietze, Seth, Cheng, Donghui, Wadsworth, Sarah, Lawson, Gregory W., Bensinger, Steven J., Farnham, Peggy J., Witte, Owen N., Smale, Stephen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800053/
https://ncbi.nlm.nih.gov/pubmed/24013668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2707
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