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Regulation of VDR expression in Apc mutant mice, human colon cancers and adenomas
One variable that may impact the ability of vitamin D to reduce colon cancer risk is the expression of its high affinity receptor, VDR. Here we show that vitamin D does not reduce tumor formation in Apc(Δ14/+) mice and that VDR expression is lost in the majority of the colon tumor cells. The extent...
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| Publicado no: | Cancer Prev Res (Phila) |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417398/ https://ncbi.nlm.nih.gov/pubmed/25873367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0371 |
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