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Aldosterone-induced Sgk1 relieves Dot1a-Af9–mediated transcriptional repression of epithelial Na(+) channel α
Aldosterone plays a major role in the regulation of salt balance and the pathophysiology of cardiovascular and renal diseases. Many aldosterone-regulated genes — including that encoding the epithelial Na(+) channel (ENaC), a key arbiter of Na(+) transport in the kidney and other epithelia — have bee...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1804379/ https://ncbi.nlm.nih.gov/pubmed/17332896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29850 |
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