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SGK1-dependent ENaC processing and trafficking in mice with high dietary K intake and elevated aldosterone
We examined renal Na and K transporters in mice with deletions in the gene encoding the aldosterone-induced protein SGK1. The knockout mice were hyperkalemic, and had altered expression of the subunits of the epithelial Na channel (ENaC). The kidneys showed decreased expression of the cleaved forms...
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| Udgivet i: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283884/ https://ncbi.nlm.nih.gov/pubmed/27413200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00257.2016 |
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