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SGK1-dependent ENaC processing and trafficking in mice with high dietary K intake and elevated aldosterone
We examined renal Na and K transporters in mice with deletions in the gene encoding the aldosterone-induced protein SGK1. The knockout mice were hyperkalemic, and had altered expression of the subunits of the epithelial Na channel (ENaC). The kidneys showed decreased expression of the cleaved forms...
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| 發表在: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283884/ https://ncbi.nlm.nih.gov/pubmed/27413200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00257.2016 |
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