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Expression and phosphorylation of the Na(+)-Cl(−) cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1

The Na-Cl cotransporter NCC is expressed in the distal convoluted tubule, activated by phosphorylation, and has been implicated in renal NaCl and K(+) homeostasis. The serum and glucocorticoid inducible kinase 1 (SGK1) contributes to renal NaCl retention and K(+) excretion, at least in part, by stim...

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Bibliographic Details
Main Authors: Vallon, Volker, Schroth, Jana, Lang, Florian, Kuhl, Dietmar, Uchida, Shinichi
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739704/
https://ncbi.nlm.nih.gov/pubmed/19570885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00030.2009
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