A cooperative oxygen-binding hemoglobin from Mycobacterium tuberculosis

Two putative hemoglobin genes, glbN and glbO, were recently discovered in the complete genome sequence of Mycobacterium tuberculosis H37Rv. Here, we show that the glbN gene encodes a dimeric hemoglobin (HbN) that binds oxygen cooperatively with very high affinity (P(50) = 0.013 mmHg at 20°C) because...

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Detaylı Bibliyografya
Asıl Yazarlar: Couture, Manon, Yeh, Syun-Ru, Wittenberg, Beatrice A., Wittenberg, Jonathan B., Ouellet, Yannick, Rousseau, Denis L., Guertin, Michel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC18015/
https://ncbi.nlm.nih.gov/pubmed/10500158
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