A cooperative oxygen-binding hemoglobin from Mycobacterium tuberculosis

Two putative hemoglobin genes, glbN and glbO, were recently discovered in the complete genome sequence of Mycobacterium tuberculosis H37Rv. Here, we show that the glbN gene encodes a dimeric hemoglobin (HbN) that binds oxygen cooperatively with very high affinity (P(50) = 0.013 mmHg at 20°C) because...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Couture, Manon, Yeh, Syun-Ru, Wittenberg, Beatrice A., Wittenberg, Jonathan B., Ouellet, Yannick, Rousseau, Denis L., Guertin, Michel
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1999
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11223
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