A cooperative oxygen-binding hemoglobin from Mycobacterium tuberculosis

Two putative hemoglobin genes, glbN and glbO, were recently discovered in the complete genome sequence of Mycobacterium tuberculosis H37Rv. Here, we show that the glbN gene encodes a dimeric hemoglobin (HbN) that binds oxygen cooperatively with very high affinity (P(50) = 0.013 mmHg at 20°C) because...

Popoln opis

Bibliografske podrobnosti

izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Couture, Manon, Yeh, Syun-Ru, Wittenberg, Beatrice A., Wittenberg, Jonathan B., Ouellet, Yannick, Rousseau, Denis L., Guertin, Michel
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1999
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11223
Oznake:	Označite Brez oznak, prvi označite!