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p18(Ink4c), but Not p27(Kip1), Collaborates with Men1 To Suppress Neuroendocrine Organ Tumors
Mutant mice lacking both cyclin-dependent kinase (CDK) inhibitors p18(Ink4c) and p27(Kip1) develop a tumor spectrum reminiscent of human multiple endocrine neoplasia (MEN) syndromes. To determine how p18 and p27 genetically interact with Men1, the tumor suppressor gene mutated in familial MEN1, we c...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800728/ https://ncbi.nlm.nih.gov/pubmed/17145768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01764-06 |
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