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Pituitary Hyperplasia in Glycoprotein Hormone Alpha Subunit-, p18(INK4C)-, and p27(kip-1)-Null Mice : Analysis of Proteins Influencing p27(kip-1) Ubiquitin Degradation
Most spontaneously developing hyperplastic and neoplastic lesions of the pituitary occur in the anterior pituitary. Targeted disruption of various cell-cycle proteins, including Rb, p27(kip1) (p27), and p18(INK4c) (p18), is associated with intermediate lobe pituitary hyperplasia. To develop a model...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Investigative Pathology
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1867195/ https://ncbi.nlm.nih.gov/pubmed/11891212 |
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