A carregar...
Loss of Hsp90 Association Up-Regulates Src-Dependent ErbB2 Activity
The receptor tyrosine kinase ErbB2 plays a crucial role in tumorigenesis. We showed previously that the molecular chaperone Hsp90 protects ErbB2 from proteasome-mediated degradation by binding to a short loop structure in the N-lobe of the kinase domain. Here we show that loss of Hsp90 binding corre...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800645/ https://ncbi.nlm.nih.gov/pubmed/17030621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00899-06 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|