Decreased activity of UMP pyrophosphorylase associated with resistance to 5-fluorocytosine in Candida albicans.

UMP pyrophosphorylase activity was assayed in crude lysates prepared from Candida albicans. Specific activity of UMP pyrophosphorylase was high in clinical isolates which were susceptible to 5-fluorocytosine. Resistant clinical isolates displayed low activity, and partially resistant (heterozygous)...

Полное описание

Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Whelan, W L, Kerridge, D
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1984
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6393861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.4.570
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