Decreased activity of UMP pyrophosphorylase associated with resistance to 5-fluorocytosine in Candida albicans.

UMP pyrophosphorylase activity was assayed in crude lysates prepared from Candida albicans. Specific activity of UMP pyrophosphorylase was high in clinical isolates which were susceptible to 5-fluorocytosine. Resistant clinical isolates displayed low activity, and partially resistant (heterozygous)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Whelan, W L, Kerridge, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1984
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC179965/
https://ncbi.nlm.nih.gov/pubmed/6393861
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