Decreased activity of UMP pyrophosphorylase associated with resistance to 5-fluorocytosine in Candida albicans.
UMP pyrophosphorylase activity was assayed in crude lysates prepared from Candida albicans. Specific activity of UMP pyrophosphorylase was high in clinical isolates which were susceptible to 5-fluorocytosine. Resistant clinical isolates displayed low activity, and partially resistant (heterozygous)...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6393861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.26.4.570 |
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