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Expression of transforming growth factor‐β (TGFβ) and the TGFβ signalling molecule SMAD‐2P in spontaneous and instability‐induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation

BACKGROUND: The primary feature of osteoarthritis is cartilage loss. In addition, osteophytes can frequently be observed. Transforming growth factor‐β (TGFβ) has been suggested to be associated with protection against cartilage damage and new cartilage formation as seen in osteophytes. OBJECTIVE: To...

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書誌詳細
主要な著者: Davidson, E N Blaney, Vitters, E L, van der Kraan, P M, van den Berg, W B
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Group 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798346/
https://ncbi.nlm.nih.gov/pubmed/16439443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.045971
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