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Expression of transforming growth factor‐β (TGFβ) and the TGFβ signalling molecule SMAD‐2P in spontaneous and instability‐induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation

BACKGROUND: The primary feature of osteoarthritis is cartilage loss. In addition, osteophytes can frequently be observed. Transforming growth factor‐β (TGFβ) has been suggested to be associated with protection against cartilage damage and new cartilage formation as seen in osteophytes. OBJECTIVE: To...

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Bibliografski detalji
Glavni autori: Davidson, E N Blaney, Vitters, E L, van der Kraan, P M, van den Berg, W B
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798346/
https://ncbi.nlm.nih.gov/pubmed/16439443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.045971
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