Expression of transforming growth factor‐β (TGFβ) and the TGFβ signalling molecule SMAD‐2P in spontaneous and instability‐induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation

BACKGROUND: The primary feature of osteoarthritis is cartilage loss. In addition, osteophytes can frequently be observed. Transforming growth factor‐β (TGFβ) has been suggested to be associated with protection against cartilage damage and new cartilage formation as seen in osteophytes. OBJECTIVE: To...

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Détails bibliographiques
Auteurs principaux: Davidson, E N Blaney, Vitters, E L, van der Kraan, P M, van den Berg, W B
Format: Artigo
Langue:Inglês
Publié: BMJ Group 2006
Sujets:
Extended Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798346/
https://ncbi.nlm.nih.gov/pubmed/16439443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.045971
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