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Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

Chronic exposure of pancreatic islets to supraphysiologic concentrations of glucose causes adverse alterations in β cell function, a phenomenon termed glucose toxicity and one that may play a secondary pathogenic role in type 2 diabetes. However, no mechanism of action has been definitively identifi...

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Autors principals: Tanaka, Yoshito, Gleason, Catherine E., Tran, Phuong Oanh T., Harmon, Jamie S., Robertson, R. Paul
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17973/
https://ncbi.nlm.nih.gov/pubmed/10485916
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