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Herpes simplex virus eliminates host mitochondrial DNA

Mitochondria have crucial roles in the life and death of mammalian cells, and help to orchestrate host antiviral defences. Here, we show that the ubiquitous human pathogen herpes simplex virus (HSV) induces rapid and complete degradation of host mitochondrial DNA during productive infection of cultu...

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Detalhes bibliográficos
Main Authors: Saffran, Holly A, Pare, Justin M, Corcoran, Jennifer A, Weller, Sandra K, Smiley, James R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796774/
https://ncbi.nlm.nih.gov/pubmed/17186027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400878
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