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Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon

Interferon (IFN) is an important immune system molecule capable of inducing an antiviral state within cells. Herpes simplex virus type 1 (HSV-1) replication is somewhat reduced in tissue culture in the presence of IFN, presumably due to decreased viral transcription. Here, we show mutations that ina...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Mossman, Karen L., Saffran, Holly A., Smiley, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10644380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.4.2052-2056.2000
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