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Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon

Interferon (IFN) is an important immune system molecule capable of inducing an antiviral state within cells. Herpes simplex virus type 1 (HSV-1) replication is somewhat reduced in tissue culture in the presence of IFN, presumably due to decreased viral transcription. Here, we show mutations that ina...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Mossman, Karen L., Saffran, Holly A., Smiley, James R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10644380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.4.2052-2056.2000
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