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Herpes Simplex Virus ICP0 Mutants Are Hypersensitive to Interferon

Interferon (IFN) is an important immune system molecule capable of inducing an antiviral state within cells. Herpes simplex virus type 1 (HSV-1) replication is somewhat reduced in tissue culture in the presence of IFN, presumably due to decreased viral transcription. Here, we show mutations that ina...

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Bibliografiske detaljer
Main Authors: Mossman, Karen L., Saffran, Holly A., Smiley, James R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111685/
https://ncbi.nlm.nih.gov/pubmed/10644380
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