Načítá se...

RNAi-Mediated Simultaneous Downregulation of uPAR and Cathepsin B Induces Caspase 8-Mediated Apoptosis in SNB19 Human Glioma Cells

The invasive character of gliomas depends on proteolytic cleavage of the surrounding extracellular matrix. Cathepsin B and uPAR together are known to be overexpressed in gliomas, and as such, are attractive targets for gene therapy. In the present study, we used plasmid constructs to induce the RNAi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gondi, Christopher S, Kandhukuri, Neelima, Kondraganti, Shakuntala, Gujrati, Meena, Olivero, William C., Dinh, Dzung H., Rao, Jasti S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794683/
https://ncbi.nlm.nih.gov/pubmed/17172424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-05-0531
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!