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RNAi-mediated Downregulation of MMP-2 Activates the Extrinsic Apoptotic Pathway in Human Glioma Xenograft Cells

Malignant gliomas are characterized by invasive and infiltrative behavior that generally involves the destruction of normal brain tissue. Strategies to treat infiltrating gliomas, such as chemotherapy and gene therapy, have remained largely unsuccessful. The infiltrative nature of gliomas can be att...

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Bibliographische Detailangaben
Hauptverfasser: Gondi, Christopher S., Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739107/
https://ncbi.nlm.nih.gov/pubmed/19724922
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