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Simultaneous downregulation of uPAR and MMP-9 induces the overexpression of FADD-associated protein RIP and activates caspase 9-mediated apoptosis in gliomas

We have previously demonstrated the effectiveness of simultaneous RNAi-mediated downregulation of urokinase-type plasminogen activator receptor (uPAR) and matrix metalloproteinase-9 (MMP-9) in inhibiting tumor invasion in vitro and in vivo. In particular, we have shown that the downregulation of uPA...

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Detalles Bibliográficos
Main Authors: Gondi, Christopher S., Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562615/
https://ncbi.nlm.nih.gov/pubmed/18813792
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