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Simultaneous downregulation of uPAR and MMP-9 induces the overexpression of FADD-associated protein RIP and activates caspase 9-mediated apoptosis in gliomas
We have previously demonstrated the effectiveness of simultaneous RNAi-mediated downregulation of urokinase-type plasminogen activator receptor (uPAR) and matrix metalloproteinase-9 (MMP-9) in inhibiting tumor invasion in vitro and in vivo. In particular, we have shown that the downregulation of uPA...
Kaydedildi:
| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562615/ https://ncbi.nlm.nih.gov/pubmed/18813792 |
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