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Downregulation of uPAR and uPA activates caspase mediated apoptosis, inhibits the PI3k/AKT pathway

Urokinase plasminogen activator (uPA) and its receptor (uPAR) play a major role in invasion and proliferation. A growing body of evidence has suggested that the uPA system promotes tumor metastasis by several different mechanisms, and not just solely by breaking down the ECM. In this study we have u...

詳細記述

保存先:
書誌詳細
主要な著者: Gondi, Christopher S, Kandhukuri, Neelima, Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905845/
https://ncbi.nlm.nih.gov/pubmed/17549401
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