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Downregulation of uPAR and uPA activates caspase mediated apoptosis, inhibits the PI3k/AKT pathway
Urokinase plasminogen activator (uPA) and its receptor (uPAR) play a major role in invasion and proliferation. A growing body of evidence has suggested that the uPA system promotes tumor metastasis by several different mechanisms, and not just solely by breaking down the ECM. In this study we have u...
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| Glavni autori: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905845/ https://ncbi.nlm.nih.gov/pubmed/17549401 |
| Oznake: |
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