Loading...

Downregulation of uPAR and uPA activates caspase mediated apoptosis, inhibits the PI3k/AKT pathway

Urokinase plasminogen activator (uPA) and its receptor (uPAR) play a major role in invasion and proliferation. A growing body of evidence has suggested that the uPA system promotes tumor metastasis by several different mechanisms, and not just solely by breaking down the ECM. In this study we have u...

Full description

Saved in:
Bibliographic Details
Main Authors: Gondi, Christopher S, Kandhukuri, Neelima, Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905845/
https://ncbi.nlm.nih.gov/pubmed/17549401
Tags: Add Tag
No Tags, Be the first to tag this record!