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Interaction of calicheamicin γ(1)(I )and its related carbohydrates with DNA–protein complexes

We report studies of the contribution of DNA structure, holding the sequence constant, to the affinity of calicheamicin γ(1)(I) and its aryltetrasaccharide moiety for DNA. We used polynucleotide chains as models of known protein-binding sequences [the catabolite activator protein (CAP) consensus seq...

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Bibliographic Details
Main Authors: Sissi, Claudia, Aiyar, Jayshree, Boyer, Serge, Depew, Kris, Danishefsky, Samuel, Crothers, Donald M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17936/
https://ncbi.nlm.nih.gov/pubmed/10485879
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