Interaction of calicheamicin γ(1)(I )and its related carbohydrates with DNA–protein complexes

We report studies of the contribution of DNA structure, holding the sequence constant, to the affinity of calicheamicin γ(1)(I) and its aryltetrasaccharide moiety for DNA. We used polynucleotide chains as models of known protein-binding sequences [the catabolite activator protein (CAP) consensus seq...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sissi, Claudia, Aiyar, Jayshree, Boyer, Serge, Depew, Kris, Danishefsky, Samuel, Crothers, Donald M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10485879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.19.10643
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