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The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

PTEN is a recently identified tumor suppressor inactivated in a variety of cancers such as glioblastoma and endometrial and prostate carcinoma. It contains an amino-terminal phosphatase domain and acts as a phosphatidylinositol 3,4,5-trisphosphate phosphatase antagonizing the activity of the phospha...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Georgescu, Maria-Magdalena, Kirsch, Kathrin H., Akagi, Tsuyoshi, Shishido, Tomoyuki, Hanafusa, Hidesaburo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC17863/
https://ncbi.nlm.nih.gov/pubmed/10468583
Tagiau: Ychwanegu Tag
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