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Biological Effects of c-Mer Receptor Tyrosine Kinase in Hematopoietic Cells Depend on the Grb2 Binding Site in the Receptor and Activation of NF-κB

The c-Mer receptor tyrosine kinase (RTK) is most closely related to chicken c-Eyk and belongs to the Axl RTK subfamily. Although not detected in normal lymphocytes, c-Mer is expressed in B- and T-cell leukemia cell lines, suggesting an association with lymphoid malignancies. To gain an understanding...

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Bibliografische gegevens
Hoofdauteurs: Georgescu, Maria-Magdalena, Kirsch, Kathrin H., Shishido, Tomoyuki, Zong, Chen, Hanafusa, Hidesaburo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC116046/
https://ncbi.nlm.nih.gov/pubmed/9891051
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