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Polymerization of fibrin: direct observation and quantification of individual B:b knob-hole interactions

The polymerization of fibrin occurs primarily through interactions between N-terminal A- and B-knobs, which are exposed by the cleavage of fibrinopeptides A and B, respectively, and between corresponding a- and b-holes in the γ- and β-modules. Of the potential knob-hole interactions—A:a, B:b, A:b, a...

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Autori principali: Litvinov, Rustem I., Gorkun, Oleg V., Galanakis, Dennis K., Yakovlev, Sergiy, Medved, Leonid, Shuman, Henry, Weisel, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785071/
https://ncbi.nlm.nih.gov/pubmed/16940416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-033910
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