Molecular Mechanisms, Thermodynamics, and Dissociation Kinetics of Knob-Hole Interactions in Fibrin

Polymerization of fibrin, the primary structural protein of blood clots and thrombi, occurs through binding of knobs ‘A’ and ‘B’ in the central nodule of fibrin monomer to complementary holes ‘a’ and ‘b’ in the γ- and β-nodules, respectively, of another monomer. We characterized the A:a and B:b knob...

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Detaylı Bibliyografya
Asıl Yazarlar: Kononova, Olga, Litvinov, Rustem I., Zhmurov, Artem, Alekseenko, Andrey, Cheng, Chia Ho, Agarwal, Silvi, Marx, Kenneth A., Weisel, John W., Barsegov, Valeri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Molecular Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829353/
https://ncbi.nlm.nih.gov/pubmed/23720752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472365
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