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Misfolded Proteins Traffic from the Endoplasmic Reticulum (ER) Due to ER Export Signals

Most misfolded secretory proteins remain in the endoplasmic reticulum (ER) and are degraded by ER-associated degradation (ERAD). However, some misfolded proteins exit the ER and traffic to the Golgi before degradation. Using model misfolded substrates, with or without defined ER exit signals, we fou...

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Bibliografiska uppgifter
Huvudupphovsmän: Kincaid, Margaret M., Cooper, Antony A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783784/
https://ncbi.nlm.nih.gov/pubmed/17108324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0696
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