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Misfolded Proteins Traffic from the Endoplasmic Reticulum (ER) Due to ER Export Signals
Most misfolded secretory proteins remain in the endoplasmic reticulum (ER) and are degraded by ER-associated degradation (ERAD). However, some misfolded proteins exit the ER and traffic to the Golgi before degradation. Using model misfolded substrates, with or without defined ER exit signals, we fou...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783784/ https://ncbi.nlm.nih.gov/pubmed/17108324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0696 |
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