Export of a Cysteine-Free Misfolded Secretory Protein from the Endoplasmic Reticulum for Degradation Requires Interaction with Protein Disulfide Isomerase

Protein disulfide isomerase (PDI) interacts with secretory proteins, irrespective of their thiol content, late during translocation into the ER; thus, PDI may be part of the quality control machinery in the ER. We used yeast pdi1 mutants with deletions in the putative peptide binding region of the m...

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Bibliografske podrobnosti
Main Authors: Gillece, Pauline, Luz, José Manuel, Lennarz, William J., de la Cruz, Francisco Javier, Römisch, Karin
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1999
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174254/
https://ncbi.nlm.nih.gov/pubmed/10613903
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