Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress

The endoplasmic reticulum (ER) is responsible for protein folding, modification, and trafficking. Accumulation of unfolded or misfolded proteins represents the condition of ER stress and triggers the unfolded protein response (UPR), a key mechanism linking supply of excess nutrients to insulin resis...

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Detalhes bibliográficos
Main Authors: Lee, Samuel, Min Kim, Soo, Dotimas, James, Li, Letitia, Feener, Edward P, Baldus, Stephan, Myers, Ronald B, Chutkow, William A, Patwari, Parth, Yoshioka, Jun, Lee, Richard T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203352/
https://ncbi.nlm.nih.gov/pubmed/24843047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201302561
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