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Misfolded Proteins Traffic from the Endoplasmic Reticulum (ER) Due to ER Export Signals
Most misfolded secretory proteins remain in the endoplasmic reticulum (ER) and are degraded by ER-associated degradation (ERAD). However, some misfolded proteins exit the ER and traffic to the Golgi before degradation. Using model misfolded substrates, with or without defined ER exit signals, we fou...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Cell Biology
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783784/ https://ncbi.nlm.nih.gov/pubmed/17108324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0696 |
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