Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids

Lignende værker

• Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA
  af: Sarafianos, Stefan G., et al.
  Udgivet: (2001)
• YADD Mutants of Human Immunodeficiency Virus Type 1 and Moloney Murine Leukemia Virus Reverse Transcriptase Are Resistant to Lamivudine Triphosphate (3TCTP) In Vitro
  af: Boyer, Paul L., et al.
  Udgivet: (2001)
• Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA
  af: Sarafianos, Stefan G., et al.
  Udgivet: (2002)
• Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition
  af: Sarafianos, Stefan G., et al.
  Udgivet: (2008)
• Selective Excision of AZTMP by Drug-Resistant Human Immunodeficiency Virus Reverse Transcriptase
  af: Boyer, Paul L., et al.
  Udgivet: (2001)