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Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105–125
To identify sequence domains important for the neurotoxic and neuroprotective activities of the prion protein (PrP), we have engineered transgenic mice that express a form of murine PrP deleted for a conserved block of 21 amino acids (residues 105–125) in the unstructured, N-terminal tail of the pro...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783448/ https://ncbi.nlm.nih.gov/pubmed/17245437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601507 |
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